https://gcc.gnu.org/bugzilla/show_bug.cgi?id=101378
--- Comment #1 from Simon Marchi <simon.marchi at polymtl dot ca> --- I bisected, it started with: libstdc++: Remove inheritance from elements in std::tuple 91e6226f880b048275a7ceedef716e159c7cefd9 So it's likely related to the use of [[no_unique_address]]. Relevant thread on dwarf-discuss: http://lists.dwarfstd.org/pipermail/dwarf-discuss-dwarfstd.org/2021-June/004825.html