https://gcc.gnu.org/bugzilla/show_bug.cgi?id=82618
--- Comment #1 from Jakub Jelinek <jakub at gcc dot gnu.org> --- Or add a pattern for (set (reg:DI 100) (subreg:DI (minus:TI (reg/v:TI 90 [ x ]) (reg/v:TI 94 [ y ])) 8)) that combine would match and then reload that differently if not using SSE regs and split it differently too.