Hi, The system on which it i occurring is a Debian Buster 10.3 The binaries that are involved are provided by the following packages: ii ncbi-blast+ 2.8.1-1 amd64 next generation suite of BLAST sequence search tools ii ncbi-blast+-legacy 2.8.1-1 all NCBI Blast legacy call script
and here is what dmesg says: [16950090.751977] traps: blastn[8041] trap invalid opcode ip:7f1a5e4ce98c sp:7ffe69e29be0 error:0 in libblast.so[7f1a5e48d000+66000] [16951820.852031] traps: blastn[8512] trap invalid opcode ip:7fd312fed98c sp:7ffe840c5780 error:0 in libblast.so[7fd312fac000+66000] [16952207.586375] traps: makeblastdb[8966] trap invalid opcode ip:7faa9aaa6b02 sp:7ffe4ff58040 error:0 in libxutil.so[7faa9aa73000+83000] [16952218.407194] traps: makeblastdb[8975] trap invalid opcode ip:7f8a2ac08b02 sp:7ffc88589580 error:0 in libxutil.so[7f8a2abd5000+83000] May some amd64 packages supposed to be executable only for specific CPU/arch? Here is the hardware information: LANG=C lshw -short H/W path Device Class Description ============================================================== system PowerEdge 6850 /0 bus 0RD318 /0/0 memory 64KiB BIOS /0/400 processor Intel(R) Xeon(TM) CPU 3.40GHz /0/400/700 memory 32KiB L1 cache /0/400/701 memory 2MiB L2 cache /0/400/702 memory 16MiB L3 cache /0/401 processor Intel(R) Xeon(TM) CPU 3.40GHz /0/401/703 memory 32KiB L1 cache /0/401/704 memory 2MiB L2 cache /0/401/705 memory 16MiB L3 cache /0/402 processor Intel(R) Xeon(TM) CPU 3.40GHz /0/402/706 memory 32KiB L1 cache /0/402/707 memory 2MiB L2 cache /0/402/708 memory 16MiB L3 cache /0/403 processor Intel(R) Xeon(TM) CPU 3.40GHz /0/403/709 memory 32KiB L1 cache /0/403/70a memory 2MiB L2 cache /0/403/70b memory 16MiB L3 cache /0/1000 memory 64GiB System Memory ... Thanks, Patrice