Package: wnpp Severity: wishlist Owner: Steffen Moeller <moel...@debian.org> X-Debbugs-Cc: debian-devel@lists.debian.org, moel...@debian.org
* Package name : pvactools Version : 5.4.3 * URL : https://github.com/griffithlab/pVACtools * License : BSD Programming Lang: Python Description : cancer immunotherapy suite This package aims at supporting the immune system to recognize tumor tissue as foreign. The basic idea is to learn from DNA sequencing about differences that the tumor has in its protein sequences. And if the patient is likely to recognize such linear fragments as forein if pushed a bit, then can possibly start to think about vaccinating with these fragments. . pVACtools is a cancer immunotherapy suite consisting of the following tools: . pVACseq: A cancer immunotherapy pipeline for identifying and prioritizing neoantigens from a VCF file. . pVACbind: A cancer immunotherapy pipeline for identifying and prioritizing neoantigens from a FASTA file. . pVACfuse: A tool for detecting neoantigens resulting from gene fusions. . pVACsplice: A tool for detecting neoantigens resulting from splice site variants. . pVACvector: A tool designed to aid specifically in the construction of DNA vector-based cancer vaccines. . pVACview: An application based on R Shiny that assists users in reviewing, exploring and prioritizing neoantigens from the results of pVACtools processes for personalized cancer vaccine design. I am not ultimately confident that this package will every surface in Debian, let alone since with its 1.8 GB it is rather massive. But there are a series of dependencies that Debian should offer to its biomedical research community that I want to see in our distribution: python3-mhcflurry, python3-mhcnuggets, python3-polars, python3-simanneal, python3-varcode, python3-vaxrank, python3-vcfpy All these packages shall eventually appear on the Debian Med salsa repository.
