Package: wnpp Severity: wishlist Owner: Andreas Tille <ti...@debian.org>
* Package name : pirs Version : 2.0.2 Upstream Author : BGI * URL : https://github.com/galaxy001/pirs * License : BSD Programming Lang: C++ Description : Profile based Illumina pair-end Reads Simulator The program pIRS can be used for simulating Illumina PE reads, with a series of characters generated by Illumina sequencing platform, such as insert size distribution, sequencing error(substitution, insertion, deletion), quality score and GC content-coverage bias. . The insert size follows a normal distribution, so users should set the mean value and standard deviation. Usually the standard deviation is set as 1/20 of the mean value. The normal distribution by Box-Muller method is simulated. . The program simulates sequencing error, quality score and GC content- coverage bias according to the empirical distribution profile. Some default profiles counted from lots of real sequencing data are provided. . To simulate reads from diploid genome, users should simulate the diploid genome sequence firstly by setting the ratio of heterozygosis SNP, heterozygosis InDel and structure variation.
