Package: wnpp Severity: wishlist Owner: Steffen Moeller <steffen_moel...@gmx.de>
* Package name : r-other-mott-happy Version : 2.1 Upstream Author : Richard Mott <richard.m...@well.ox.ac.uk> * URL : http://www.well.ox.ac.uk/happy/happyR.shtml. * License : GPL-2+ Programming Lang: C,R Description : GNU R package for fine-mapping complex diseases The idea behind this package is that when multiple strains of animals that differ in their susceptibility to multiple diseases are bread over multiple generations, then one can analyse the contribution that a particular genetic locus has to each of those diseases. While in the past this approach has been performed for one disease at a time, this tool extends the statistics for allowing multiple crosses and thus save animal lifes. A larger stock of animals with more generations to keep them will further help producing larger numbers of observable cross-over events and thus help increasing the resolution of the mapping. . happy is an R interface into the HAPPY C package for fine-mapping Quantitative Trait Loci (QTL) in Heterogenous Stocks (HS). An HS is an advanced intercross between (usually eight) founder inbred strains of mice. HS are suitable for fine-mapping QTL. The happy package is an extension of the original C program happy; it uses the C code to compute the probability of descent from each of the founders, at each locus position, but the happy packager allows a much richer range of models to be fit to the data. -- To UNSUBSCRIBE, email to debian-devel-requ...@lists.debian.org with a subject of "unsubscribe". Trouble? Contact listmas...@lists.debian.org
