I can reproduce this. The reason is that pyspread uses the cairo component from the package python-wxgtk3.0 that has been broken. This bug affects all Cairo based applications that use wxPython (e.g. the wxPython demo).
- Bug#883741: pyspread: Spreadsheet canvas won't show with new... Lorenz Minder
- Bug#883741: pyspread: Spreadsheet canvas won't show wit... Martin Manns
- Bug#883741: pyspread: Spreadsheet canvas won't show wit... Martin Manns
- Bug#883741: pyspread: Spreadsheet canvas won't show wit... Martin Manns