Deleted my ~/.gconf* ~/.gtk* ~/.gnome-* (excluding desktop of course :) ) etc. etc. and then logged in and started sylpheed - Ctrl+Click now works.
Sylpheed was only application affected - I'm wondering if it was something GTK. Either way, I guess it's one way of getting motivation to clean out my Gnome and friends config :) -- To UNSUBSCRIBE, email to [EMAIL PROTECTED] with a subject of "unsubscribe". Trouble? Contact [EMAIL PROTECTED]