After reviewing the contents of /etc/network/interfaces.d/50-cloud-init containing the call to the missing route command it occurred to me that this may be an issue with cloud-init instead.
- Bug#1040867: ifupdown: ifup exits with /bin/sh: 1: route: no... Nate Childers
- Bug#1040867: bug#1040867 could be with cloud-init rathe... Nate Childers
