I've got a similar problem, using repositories on deb.debian,org. 'apt update' fails to obtain the InRelease files from acng:
: Ign:18 http://HTTPS///pkg.jenkins.io/debian binary/ InRelease Hit:19 http://HTTPS///pkg.jenkins.io/debian binary/ Release Err:21 http://deb.debian.org/debian bullseye InRelease Connection failed [IP: 172.19.96.126 3142] Err:22 http://deb.debian.org/debian bullseye-updates InRelease Connection failed [IP: 172.19.96.126 3142] Err:23 http://deb.debian.org/debian bullseye-proposed-updates InRelease Connection failed [IP: 172.19.96.126 3142] Fetched 9383 B in 3min 0s (52 B/s) Reading package lists... Done Building dependency tree... Done Reading state information... Done : /var/log/apt-cacher-ng/apt-cacher.err shows Tue Aug 31 10:16:45 2021|Failed to move stale item debrep/dists/buster/InRelease out of the way: No such file or directory Tue Aug 31 10:16:51 2021|Failed to move stale item debrep/dists/bullseye/InRelease out of the way: No such file or directory Tue Aug 31 10:17:45 2021|Failed to move stale item debrep/dists/buster-updates/InRelease out of the way: No such file or directory Tue Aug 31 10:17:51 2021|Failed to move stale item debrep/dists/bullseye-updates/InRelease out of the way: No such file or directory Tue Aug 31 10:18:11 2021|Failed to move stale item debrep/dists/bullseye/InRelease out of the way: No such file or directory Tue Aug 31 10:18:45 2021|Failed to move stale item debrep/dists/buster-proposed-updates/InRelease out of the way: No such file or directory Tue Aug 31 10:18:51 2021|Failed to move stale item debrep/dists/bullseye-proposed-updates/InRelease out of the way: No such file or directory Regards Harri