Given some other experiences with amdgpu modesetting problems, and looking at this bug, I would say:-
1) Please try updating all packages and reboot and try again, kernel should be now 4.19.0-16 2) Secondly, enable backports https://backports.debian.org/Instructions/ and then:- apt-get -t buster-backports install linux-image-amd64 linux-headers-amd64 This should get you a 5.10 series kernel. My strong experience with amdgpu has been that a whole lot of modesetting, sleep, etc etc. issues are massively improved in 5.10 kernel series of late, irrespective of the xserver-xorg version in use. NB: At boot-time, in normal cases, GRUB menu should allow you to 'select' which kernel you boot into i.e you should be able to select between 5.10.0.bpo.?? and 4.19.0-16 kernel. I note, the backports kernel is lagging behind a little, hopefully 5.10.0-0.bpo.6 and 5.10.0-0.bpo.7 will come out soon. --Simon