Since upgrade to buster, I've been seeing the same behavior as reported in this bug. Not sure if it needs a new bug. Decided on replying to existing bug since this one was left unreproducible, but my system seems to have found a way... Running XFCE with "Enable assistive technologies" unchecked in xfce4-accessibility-settings. The same error as in the report happens with reportbug, exo-open, exo-helper, vlc, mousepad, xarchiver, etc.
Other GTK apps (e.g. gimp, ristretto, xournal) report a different message that may be related: Gtk-Message: 12:34:56.789: Failed to load module "atk-bridge" Please find below various system info. Note the tmp filenames, userid, and guids have been changed to bogus but consistent values. % lsb_release -da No LSB modules are available. Distributor ID: Debian Description: Debian GNU/Linux 10 (buster) Release: 10 Codename: buster % uname -r 4.19.0-5-amd64 %apt-cache policy at-spi2-core at-spi2-core: Installed: 2.30.0-7 Candidate: 2.30.0-7 Version table: *** 2.30.0-7 500 500 https://deb.debian.org/debian buster/main amd64 Packages 100 /var/lib/dpkg/status % ps aux|grep -i at-spi|grep -v grep xavier 895 0.0 0.0 312472 5172 ? Ssl Jul20 0:00 /usr/lib/at-spi2-core/at-spi-bus-launcher xavier 917 0.0 0.0 8968 3144 ? S Jul20 0:53 /usr/bin/dbus-daemon --config-file=/usr/share/defaults/at-spi2/accessibility.conf --nofork --print-address 3 xavier 8546 0.0 0.0 174108 5908 ? Sl Jul20 3:07 /usr/lib/at-spi2-core/at-spi2-registryd --use-gnome-session root 30144 0.0 0.0 312460 5632 ? Sl Jul20 0:00 /usr/lib/at-spi2-core/at-spi-bus-launcher root 30149 0.0 0.0 8840 2912 ? S Jul20 0:42 /usr/bin/dbus-daemon --config-file=/usr/share/defaults/at-spi2/accessibility.conf --nofork --print-address 3 root 30151 0.0 0.0 174148 6012 ? Sl Jul20 3:03 /usr/lib/at-spi2-core/at-spi2-registryd --use-gnome-session % ps aux|grep -i at-spi|grep -v grep % xprop -root | grep SPI AT_SPI_BUS(STRING) = "unix:abstract=/tmp/dbus-0XXXXXXXXX,guid=0000000000000000123456789abcdef0" % dbus-monitor --address "unix:abstract=/tmp/dbus-0XXXXXXXXX,guid=0000000000000000123456789abcdef0" Failed to register connection to bus at unix:abstract=/tmp/dbus-0XXXXXXXXX,guid=0000000000000000123456789abcdef0: Did not receive a reply. Possible causes include: the remote application did not send a reply, the message bus security policy blocked the reply, the reply timeout expired, or the network connection was broken. %echo $GTK_MODULES gail:atk-bridge %echo $OOO_FORCE_DESKTOP %echo $GNOME_ACCESSIBILITY %echo $QT_ACCESSIBILITY 1 %echo $QT_LINUX_ACCESSIBILITY_ALWAYS_ON %echo $NO_AT_BRIDGE % git clone https://git.debian.org/git/pkg-a11y/check-a11y ... % cd check-a11y % ./troubleshoot Info INFO: session type 'x11' INFO: VT '7' INFO: session desktop 'lightdm-xsession' INFO: current desktop 'XFCE' Packages PASS: at-spi2-core installed PASS: libgail-common installed FAIL: libatk-adaptor not installed, GTK2 applications will not be accessible FAIL: qt-at-spi not installed, Qt4 applications will not be accessible PASS: libatk-wrapper-java installed Running environment PASS: at-spi-bus-launcher is running as user xavier PASS: at-spi2-registryd is running as user xavier FAIL: mismatch between $DBUS_SESSION_BUS_ADDRESS (unix:path=/run/user/31337/bus) and well-known path /home/xavier/.dbus/session-bus/1111111111111111123456789abcdef0-0 (unix:abstract=/tmp/dbus-2XXXXXXXXX,guid=2222222222222222123456789abcdef0) PASS: got accessibility bus unix:abstract=/tmp/dbus-3XXXXXXXXX,guid=3333333333333333123456789abcdef0 from session dbus PASS: got accessibility bus unix:abstract=/tmp/dbus-0XXXXXXXXX,guid=0000000000000000123456789abcdef0 from root window FAIL: accessibility bus unix:abstract=/tmp/dbus-3XXXXXXXXX,guid=3333333333333333123456789abcdef0 from session dbus doesn't match accessibility bus unix:abstract=/tmp/dbus-0XXXXXXXXX,guid=0000000000000000123456789abcdef0 from root window WARN: org.a11y.Status IsEnabled is 'false', mozilla applications will not be accessible unless GNOME_ACCESSIBILITY is set to 1 Layer enabling ./troubleshoot: line 177: type: gsettings: not found WARN: GNOME_ACCESSIBILITY is set to '', mozilla applications will not be accessible unless IsEnabled is set to true (as typically set by starting orca, but not accerciser etc.) PASS: assistive technology enabled in /etc/java-8-openjdk/accessibility.properties. WARN: default Look and Feel is not GTK in /etc/java-8-openjdk/swing.properties, Java 8 Swing applications may not be accessible. WARN: assistive technology not enabled in /etc/java-11-openjdk/accessibility.properties, Java 11 Swing applications may not be accessible. WARN: default Look and Feel is not GTK in /etc/java-11-openjdk/swing.properties, Java 11 Swing applications may not be accessible.