Hello, I faced this very same issue today. googling this bug report was extremely useful: I deleted timidity, and now sound is back. Obviously this is no solution, as I (or someone else) will need timidity eventually.
I understand this is not a kernel related issue, but it is still a serious issue anyway: timidity may grab the sound card at random moments, making sound unusable. I cannot tell who is actual package (timidity? systemd?) responsible for this nor how this can be corrected (maybe insert an extra delay before the timidity daemon is started?), but it sure requires a fix. So shouldn't this bug be reassigned rather than closed? Thanks! Best, Nick