As you are using spanish localization, most probably it is the same issue that one reported in github: https://github.com/AmatCoder/mednaffe/issues/52
It is fixed in versions >= 0.8.5 of mednaffe. On Thu, 15 Feb 2018 00:47:02 -0300, Nacho <cbx...@protonmail.com> wrote: > I'm having troubles launching the GUI for mednafen (mednaffe). > Whenever I launch mednaffe, an error prompt reports: "Error: Mednafen > version is not compatible. You need 0.9.41 version or above. But then, > mednafen --version reports that the version installed from the stretch > repository is 0.9.41.